Integrative omics to study gene expression regulation Gene expression is regulated in part by the incorporation of histone variants and by the dynamic modification of histones by various chemical groups. A tight regulation of these mechanisms is necessary during cellular differentiation processes; dysregulations are at stake in numerous diseases, including...Read More
the Biomedical Proteomics group aims to develop robust proteomics pipelines for the phenotyping of patients through in-depth characterization of biofluid proteomes, the identification of new biomarkers and the improved comprehension of pathogenetic mechanisms.
Plasma biomarkers MS-based proteomics is particularly well-suited for identifying specifically and measuring accurately the abundance of protein biomarker candidates. During the last quinquennial period, EDyP team has implemented and optimized an integrated pipeline This biomarker development pipeline was harnessed internally to complete research projects in the field of hepatology (Dr...Read More