last quinquennial period (2014-2019)
Immunoassays are used for decades in clinical laboratories to quantify proteins in blood samples. However, MS-based proteomics analysis has recently appeared as a promising option to assess panels of protein biomarkers and provide protein profiles useful for health state monitoring. Nevertheless, the translation of MS-based proteomics into the clinics is...
This project aimed to push back the limits of mass range detection using Nano-Electro-Mechanical resonators (NEMS). NEMS were developed for various applications in electronics including tiny actuators and accelerometers. Their size and integration capabilities make them attractive as individual particle measurement devices. Mass sensing applications of NEMS were proposed as...
Proline Proline is a landmark software suite for quantitative proteomics allowing to collect, process, visualize and publish proteomics datasets [Bouyssié et al., Bioinformatics in revision 2019]. Proline is developed in partnership with ProFI members (Strasbourg, Toulouse) under the coordination of EDyP. Compared to existing tools, it combines in a unique...
“Exploring the Dynamics of Proteomes” (EDyP) team has been active in the field of proteomics since its foundation in 1992 by Dr Jérôme Garin as the “Chimie des Protéines” laboratory. Since then, EDyP team has continuously developed mass spectrometry (MS)-based and computational strategies to finely and comprehensively characterize proteomes, in order to provide new insights in basic biology, biotechnology and translational research. EDyP team is located in the West campus of Grenoble and is currently supported by 3 governmental institutions: CEA, Inserm and Grenoble Alpes Université. EDyP team is also part of the “Proteomics French Infrastructure” ProFI.
Exploring the Dynamics of Proteomes (EDyP),
Laboratoire Biologie à Grande Echelle (BGE),
Institut de Recherche Interdisciplinaire de Grenoble (IRIG)