Pour participer à son activité de R&D et de service à la communauté, l’équipe EDyP, localisée à Grenoble, recherche un/une ingénieur(e) d’Etudes en analyses protéomiques basées sur la spectrométrie de masse. Au sein de l’équipe EDyP (Exploration de la Dynamique des Protéomes, edyp.fr), vous mettrez en oeuvre un ensemble de techniques et méthodes analytiques et […]
We are very proud to announce the publication of the PepS microfluidic device in Analytical Chemistry
We are pleased and very proud to announce the publication of Proline in Bioinformatics. Feel free to try the software by downloading the zero installation version.
We are pleased to announce the release of ProteoRE 2.1, a user-oriented Galaxy-based instance, for the functional interpretation and exploration of proteomics data for biomedical research; This version now comprises 20 tools organized in 4 sections (data manipulation and visualization; add features/annotation; functional analysis; pathways analysis. All data sources have been updated. Three new tools […]
Identifying HBc nuclear regulatory functions Despite the existence of a preventive vaccine, chronic infections with Hepatitis B virus (HBV) remain a major health problem worldwide, and represent the first cause of liver cancer. Current clinically accepted antivirals treatments generally lead to a significant reduction of viremia in the blood of patients. However, the liver viral […]
Understanding antibiotic resistance of Francisella ssp Francisella tularensis is the causative agent in tularemia for which the high prevalence of treatment failure and relapse is a major concern. Using MS-based proteomics, we explore the proteomes of different Francisella strains to identify proteins that may contribute to reduced antibiotic susceptibility. Collaborators Patricia Renesto, Experimental Recombinant Therapy […]
Elucidating strategies developed by Toxoplasma gondii to orchestrate immune evasion and lifelong persistence in hosts Identification of parasite factors able to subvert activities of the host, principally focusing on nuclear proteins such as transcription factors, and modulation of the epigenetic status of target genes, leading to reshape the host genetic program. We aim to study […]
Immunoassays are used for decades in clinical laboratories to quantify proteins in blood samples. However, MS-based proteomics analysis has recently appeared as a promising option to assess panels of protein biomarkers and provide protein profiles useful for health state monitoring. Nevertheless, the translation of MS-based proteomics into the clinics is hampered by the complexity, the […]