News

Proline 2.0 Release

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Proline Release 2.0 New datastore architecture, separation of Instrument and Fractionnation rules, add new export formats, enhancement of PTM Sites managment and label-free quantitation, … and lots more

Data Science

Proline

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Proline Proline is a landmark software suite for quantitative proteomics allowing to collect, process, visualize and publish proteomics datasets [Bouyssié et al., Bioinformatics in revision 2019]. Proline is developed in partnership with ProFI members (Strasbourg, Toulouse) under the coordination of EDyP. Compared to existing tools, it combines in a unique software environment, efficient processing algorithms […]

Data Science

ProStaR

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ProStaR ProStaR, is devoted to the statistical analysis of label-free quantitative proteomics data produced by bottom-up LC-MS/MS experiments. Prostar project has two complementary aspects. First, it gathers numerous independent methodological research works in biostatistics to improve the processing of label-free relative quantitative proteomics data. These improvements concerns both specific processing steps (such as missing value […]

Data Science

ProteoRE

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ProteoRE The development of ProteoRE (Proteomics Research Environment) is an online research service to assist biologists/clinicians in the interpretation of their “Omics” data, including proteomics data. With the increased capabilities to produce MS-based proteomics data, the bottleneck has shifted to the functional analysis of specific proteins to the full exploitation of large protein lists by […]

Biomedical

Integrative Omics

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Integrative omics to study gene expression regulation Gene expression is regulated in part by the incorporation of histone variants and by the dynamic modification of histones by various chemical groups. A tight regulation of these mechanisms is necessary during cellular differentiation processes; dysregulations are at stake in numerous diseases, including developmental defects and cancers.  The […]

Biomedical

Plasma Biomarkers

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Plasma biomarkers MS-based proteomics is particularly well-suited for identifying specifically and measuring accurately the abundance of protein biomarker candidates. During the last quinquennial period, EDyP team has implemented and optimized an integrated pipeline This biomarker development pipeline was harnessed internally to complete research projects in the field of hepatology (Dr Virginie Brun and Dr Michel […]