Francisella tularensis

Understanding antibiotic resistance of Francisella ssp

Francisella tularensis is the causative agent in tularemia for which the high prevalence of treatment failure and relapse is a major concern. Using MS-based proteomics, we explore the proteomes of different Francisella strains to identify proteins that may contribute to reduced antibiotic susceptibility.


Patricia Renesto, Experimental Recombinant Therapy Team, TIMC-IMAG, Grenoble

EDyP project leader

Yohann Couté

INSERM engineer

Head of the Proteomic Application Department, EDyP-Service Manager


  • Siebert, C., Lindgren, H., Ferré, S., Villers, C., Boisset, S., Perard, J., … Renesto, P. (2019). Francisella tularensis: FupA mutation contributes to fluoroquinolone resistance by increasing vesicle secretion and biofilm formation. Emerging Microbes & Infections8(1), 808–822.


  • FINOVI (Grant AO12-02, 2018-2020)