{"id":257,"date":"2019-10-22T11:19:26","date_gmt":"2019-10-22T09:19:26","guid":{"rendered":"https:\/\/www.edyp.fr\/web\/?p=257"},"modified":"2025-06-17T16:12:28","modified_gmt":"2025-06-17T14:12:28","slug":"plasma-biomarkers","status":"publish","type":"post","link":"https:\/\/www.edyp.fr\/web\/2019\/10\/22\/plasma-biomarkers\/","title":{"rendered":"Plasma Biomarkers"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"257\" class=\"elementor elementor-257\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1061609 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1061609\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5096e05\" data-id=\"5096e05\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-305c82e elementor-widget elementor-widget-heading\" data-id=\"305c82e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><span class=\"ez-toc-section\" id=\"Plasma_biomarkers\"><\/span>Plasma biomarkers<span class=\"ez-toc-section-end\"><\/span><\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0549b64 elementor-widget elementor-widget-text-editor\" data-id=\"0549b64\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>MS-based proteomics is particularly well-suited for identifying specifically and measuring accurately the abundance of protein biomarker candidates. During the last quinquennial period, EDyP team has implemented and optimized an integrated pipeline<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dc49bdb elementor-widget elementor-widget-image\" data-id=\"dc49bdb\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"1024\" height=\"267\" src=\"https:\/\/www.edyp.fr\/web\/wp-content\/uploads\/2019\/10\/biomarkers_pipeline-1024x267.png\" class=\"attachment-large size-large wp-image-259\" alt=\"\" srcset=\"https:\/\/www.edyp.fr\/web\/wp-content\/uploads\/2019\/10\/biomarkers_pipeline-1024x267.png 1024w, https:\/\/www.edyp.fr\/web\/wp-content\/uploads\/2019\/10\/biomarkers_pipeline-300x78.png 300w, https:\/\/www.edyp.fr\/web\/wp-content\/uploads\/2019\/10\/biomarkers_pipeline-768x200.png 768w, https:\/\/www.edyp.fr\/web\/wp-content\/uploads\/2019\/10\/biomarkers_pipeline-830x216.png 830w, https:\/\/www.edyp.fr\/web\/wp-content\/uploads\/2019\/10\/biomarkers_pipeline-230x60.png 230w, https:\/\/www.edyp.fr\/web\/wp-content\/uploads\/2019\/10\/biomarkers_pipeline-350x91.png 350w, https:\/\/www.edyp.fr\/web\/wp-content\/uploads\/2019\/10\/biomarkers_pipeline-480x125.png 480w, https:\/\/www.edyp.fr\/web\/wp-content\/uploads\/2019\/10\/biomarkers_pipeline.png 1802w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-96ecf7e elementor-widget elementor-widget-text-editor\" data-id=\"96ecf7e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>This biomarker development pipeline was harnessed internally to complete research projects in the field of hepatology (Dr Virginie Brun and Dr Michel Jaquinod). Particularly, the protein ADH1B was identified and confirmed as a new biomarker the prognosis of acute liver failure [patent PCT\/FR2017\/050089; Pailleux et al., submitted]<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9a96209 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9a96209\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-49308da\" data-id=\"49308da\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7cabc97 elementor-widget elementor-widget-heading\" data-id=\"7cabc97\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\"><span class=\"ez-toc-section\" id=\"EDyP_project_leader\"><\/span>EDyP project leader<span class=\"ez-toc-section-end\"><\/span><\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-147d20b elementor-widget__width-initial eael-team-align-eael-team-align-default elementor-widget elementor-widget-eael-team-member\" data-id=\"147d20b\" data-element_type=\"widget\" data-widget_type=\"eael-team-member.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\n\n\t<div id=\"eael-team-member-147d20b\" class=\"eael-team-item eael-team-members-simple \">\n\t\t<div class=\"eael-team-item-inner\">\n\t\t\t<div class=\"eael-team-image\">\n\t\t\t\t<figure>\n\t\t\t\t\t\t\t\t\t<\/figure>\n\t\t\t\t\n\t\t\t\t\n\t\t\t<\/div>\n\n\t\t\t<div class=\"eael-team-content\">\n\t\t\t\t<h2 class=\"eael-team-member-name\"><span class=\"ez-toc-section\" id=\"Virginie_Brun\"><\/span>Virginie Brun<span class=\"ez-toc-section-end\"><\/span><\/h2><h3 class=\"eael-team-member-position\"><span class=\"ez-toc-section\" id=\"CEA_Researcher\"><\/span>CEA Researcher<span class=\"ez-toc-section-end\"><\/span><\/h3>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<ul class=\"eael-team-member-social-profiles\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<li class=\"eael-team-member-social-link\">\n\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/orcid.org\/0000-0002-9098-8707\" target=\"_blank\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<i aria-hidden=\"true\" class=\"eci  fontello-orcid-orcid-icon\"><\/i>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t\t\t\t\t<p class=\"eael-team-text\">EDyP Director<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-48968d8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"48968d8\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2d7f0ac\" data-id=\"2d7f0ac\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ee465d1 elementor-widget elementor-widget-text-editor\" data-id=\"ee465d1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>Image credit: <a href=\"https:\/\/pixabay.com\/fr\/users\/qimono-1962238\/?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=1813410\">Arek Socha<\/a> de <a href=\"https:\/\/pixabay.com\/fr\/?utm_source=link-attribution&amp;utm_medium=referral&amp;utm_campaign=image&amp;utm_content=1813410\">Pixabay<\/a><\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Plasma biomarkers MS-based proteomics is particularly well-suited for identifying specifically and measuring accurately the abundance of protein biomarker candidates. During the last [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":688,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[48],"tags":[44],"class_list":["post-257","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-plasma-biomarkers","tag-projects"],"_links":{"self":[{"href":"https:\/\/www.edyp.fr\/web\/wp-json\/wp\/v2\/posts\/257","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.edyp.fr\/web\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.edyp.fr\/web\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.edyp.fr\/web\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.edyp.fr\/web\/wp-json\/wp\/v2\/comments?post=257"}],"version-history":[{"count":14,"href":"https:\/\/www.edyp.fr\/web\/wp-json\/wp\/v2\/posts\/257\/revisions"}],"predecessor-version":[{"id":2297,"href":"https:\/\/www.edyp.fr\/web\/wp-json\/wp\/v2\/posts\/257\/revisions\/2297"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.edyp.fr\/web\/wp-json\/wp\/v2\/media\/688"}],"wp:attachment":[{"href":"https:\/\/www.edyp.fr\/web\/wp-json\/wp\/v2\/media?parent=257"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.edyp.fr\/web\/wp-json\/wp\/v2\/categories?post=257"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.edyp.fr\/web\/wp-json\/wp\/v2\/tags?post=257"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}